Plasmin-Induced Platelet Aggregation and Platelet Release Reaction. EFFECTS ON HEMOSTASIS
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چکیده
منابع مشابه
Plasmin-induced platelet aggregation and platelet release reaction. Effects on hemostasis.
Trypsin-activated pig plasmin and human plasmin activated by streptokinase (SK) caused aggregation of a suspension of washed platelets from human, rabbit, or pig blood. The platelet aggregation was reversible, but it was accompanied by a significant release of adenine nucleotides, serotonin, and platelet fibrinogen. Platelet fibrinogen was eventually digested. The effect of plasmin on platelets...
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Although arachidonic acid causes rabbit platelet aggregation and the release of granule contents in suspensions of washed platelets when used in concentrations of approximately 50-300 sM, higher concentrations (500 MM) cause neither aggregation nor release. Suspensions of platelets from rabbits were exposed to arachidonic acid (250 tM) for 1 5 mm, allowed to recover in the presence of PGE1 for ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1973
ISSN: 0021-9738
DOI: 10.1172/jci107345